The estimation of recurrence risks in monogenic disorders using flanking marker loci.
نویسنده
چکیده
A method is presented of calculating recurrence risks at a disease locus where there is information from flanking marker loci. This method uses output from the computer programme LIPED. Information from carrier detection tests and mutation at the disease locus can be taken into account in certain pedigrees.
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ورودعنوان ژورنال:
- Journal of medical genetics
دوره 22 1 شماره
صفحات -
تاریخ انتشار 1985